Angiotensin-converting enzyme gene and plasma protein level in Alzheimer's disease in Taiwanese
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چکیده
منابع مشابه
Angiotensin-converting enzyme gene and plasma protein level in Alzheimer's disease in Taiwanese.
BACKGROUND angiotensin-converting enzyme (ACE) gene insertion/deletion (indel) polymorphism is considered a biomarker for Alzheimer's disease (AD). However, the associations of ACE gene and protein level to AD are undetermined among Taiwanese. METHODS this study investigated 257 Taiwanese cases with AD and 137 ethnically matched controls using ACE gene indel genotype association methods with ...
متن کاملPlasma level and gene polymorphism of angiotensin-converting enzyme in relation to myocardial infarction.
BACKGROUND The angiotensin-converting enzyme (ACE) plays an important role in the production of angiotensin II and the degradation of bradykinin, two peptides involved in cardiovascular homeostasy. Presence of a polymorphism in the ACE gene (ACE Ss) has been postulated from segregation analysis of plasma ACE in families. This putative polymorphism, which strongly affects the plasma and cellular...
متن کاملAngiotensin Converting Enzyme Gene Polymorphism in Iranian Patients with Type 2 Diabetes
Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 2011
ISSN: 0002-0729,1468-2834
DOI: 10.1093/ageing/afq179